Low-Carbohydrate Diets and Testosterone: What the Evidence Shows

By Medically reviewed by Dr. Laura Buchanan, MD ·

Originally published

Short answer: A low-carbohydrate diet may support testosterone indirectly when it helps a man lose excess weight or improve metabolic health, but low carbohydrate intake does not reliably raise testosterone on its own.

The relationship is more nuanced than “low carb raises testosterone.” Body weight, insulin resistance, sleep, energy intake, protein intake, medications, illness, training load, and the cause of a low laboratory value all matter. This article focuses on testosterone in adult men; hormone evaluation in women is different.

Why Testosterone and Metabolic Health Are Connected

Testosterone production is regulated by the hypothalamus, pituitary gland, and testes. Testosterone also circulates partly bound to sex hormone-binding globulin (SHBG), so a single total-testosterone result does not always tell the whole story.

Obesity, type 2 diabetes, and metabolic syndrome are frequently associated with lower testosterone concentrations in men. A meta-analysis of testosterone and metabolic syndrome found a consistent association, while an individual-participant-data meta-analysis showed that the relationship varies with body mass index and individual metabolic factors.

Weight Loss May Matter More Than the Diet Label

For men with obesity-related low testosterone, improving the underlying metabolic state can be important. A systematic review and meta-analysis found that weight loss was associated with increases in both total and unbound testosterone, and the amount of weight lost was a major predictor of the change.

That helps explain why testosterone can improve during a low-carbohydrate or ketogenic intervention when the approach produces meaningful weight loss.

What Studies of Low-Carbohydrate Diets Actually Show

The available evidence is mixed and the studies are generally small.

  • A 2022 systematic review and meta-analysis of 27 intervention studies in healthy adult men found no consistent effect of moderate-protein low-carbohydrate diets on resting total testosterone. In the included short-term studies, very high-protein low-carbohydrate diets were associated with lower testosterone.
  • A separate review of ketogenic-diet studies reported an increase in total testosterone, particularly in very-low-calorie ketogenic interventions. The review included only seven studies, and the increase tracked strongly with weight loss, which makes it difficult to separate the effects of ketosis from the effects of losing weight.

The honest conclusion is that a low-carbohydrate diet can be a useful metabolic strategy for some people, but the effect on testosterone depends on the person and the way the diet is implemented.

Why Results Can Look Different From One Study—or Person—to Another

  • Energy balance: substantial calorie restriction and low energy availability can affect reproductive hormones.
  • Protein intake: “low carb” can describe very different protein and fat intakes.
  • Starting health: a man with obesity-related metabolic dysfunction is not the same study population as a lean athlete.
  • Duration: short adaptation studies cannot answer every long-term question.
  • Testing: time of day, illness, sleep, laboratory method, and SHBG can influence interpretation.

How Low Testosterone Should Be Evaluated

Symptoms matter, and so does confirmation. The Endocrine Society guideline recommends diagnosing hypogonadism only when compatible symptoms or signs occur with unequivocally and consistently low testosterone concentrations. It also recommends repeating a morning fasting total-testosterone measurement and evaluating the cause.

A clinician may consider repeat total testosterone, free testosterone when indicated, SHBG, luteinizing hormone, follicle-stimulating hormone, prolactin, medication effects, sleep apnea, fertility goals, and other health factors. Treatment is not determined by one number alone.

What to Do Next

If low testosterone is occurring alongside weight gain, insulin resistance, poor sleep, or other metabolic concerns, address the whole picture. Nutrition, resistance training, sleep, weight management, and treatment of contributing conditions may be part of the plan. Testosterone therapy or other medication can be appropriate for selected patients after an accurate diagnosis, a discussion of fertility, risks, benefits, and a monitoring plan.

Want a clinician-led evaluation? Explore Toward Health’s hormone care or virtual metabolic care.

Facebook
Twitter
LinkedIn
Email

Want support putting what you’ve learned into practice? Explore Community & Support →

Choose your next step.

Explore personalized care or continue learning with a self-guided course related to this topic.

Get Your Health Score™ →

Read more articles from our team

Bone Health Protocol in red beside an anatomical femur model with visible trabecular bone and Toward Health logo

Bone Health Protocol

A practical bone-health protocol covering calcium, vitamin D, vitamin K, magnesium, timing, and important cautions. Written by Dr. Laura Buchanan...

CAC, CCTA or a stress test? in bold red lettering beside an editorial illustration of a heart and CT scanner, with the Toward Health logo.

CAC, CCTA or a stress

Compare CAC scans, CCTA, HeartFlow, Cleerly and the different stress tests to understand which question each can answer.

Find more resources for your health.

Explore articles and videos by condition.

Explore Free Health Guides →

Browse by Condition

Apply Now