Physician-Led GLP-1 Off-Ramp and Weight Maintenance

Considering reducing or stopping Ozempic, Wegovy, Mounjaro, Zepbound, or another GLP-1 medication? Toward Health provides an individualized, physician-led transition plan when clinically appropriate, supported by medication review, personalized nutrition and protein targets, resistance training, appetite support, coaching, and ongoing follow-up.

Peer-Reviewed Research · Published One-Year Results

This program is HSA/FSA eligible.

GLP-1 Off-Ramp program support and healthy lifestyle

When the next step after GLP-1 treatment is unclear

  • Side effects, cost, access, or personal preference are prompting reconsideration.
  • You are concerned about appetite, weight, or strength as treatment changes.
  • You want a medically guided transition rather than an abrupt or generic approach.

The program provides individualized medication-transition planning supported by coaching, nutrition, movement, monitoring, and care coordination.

How a physician-led GLP-1 off-ramp works

There is no single off-ramp protocol for semaglutide or tirzepatide. Your physician reviews your medication, dose, response, side effects, health history, and goals before deciding whether and how treatment should change.

  • Medication-transition planning

    Treatment changes are individualized and guided by your physician.

  • Protein and strength support

    Personalized protein targets and resistance training help support strength and lean mass as weight and appetite change.

  • Appetite and weight maintenance

    Coaching, nutrition, monitoring, and follow-up help your team respond to hunger patterns and weight trends.

In the news

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  • USA TODAYVideo interview
  • MedscapeExpert commentary
  • FOX NationKennedy interview
  • NOLA.comLouisiana feature
  • Louisiana Public Broadcasting and PBSPublic TV interview
  • WWLTV, CBS New OrleansLocal news interview
  • Diet DoctorPhysician interview
  • Fox NewsExpert citation
  • Woman’s WorldMagazine feature

Real Results, Proven by Research

Our patients are losing weight and keeping it off, demonstrating that our lifestyle-first approach is outperforming medication alone in long-term success.

43lbs
Avg. Weight Loss
76%
Continued to lose weight after 12 months
1.1%
Avg A1C reduction
13mmHg
Avg Systolic Blood Pressure Reduction
1.9
Avg Medication Deprescription

Related published research

Evidence behind the broader TOWARD care model.

The GLP-1 Off-Ramp is designed around more than a medication decision. Coaching, education, monitoring, and support around appetite and food-related behaviors are part of the broader TOWARD model.

46%improved food addiction symptoms
81%improved binge eating symptoms

These percentages describe 37 participants with paired assessments in a 44-person cohort.

Important distinction: This 2025 observational study evaluated food addiction and binge eating symptoms in an employee wellness cohort. It did not evaluate GLP-1 tapering or medication discontinuation. We include it because it examines the broader support model used across Toward Health care.

Read the Peer-Reviewed Study
Graphical abstract summarizing Toward Health food addiction and binge eating research

What Most Patients Aren’t Told

GLP-1 medications like Ozempic and Wegovy can be powerful tools, but they come with real risks most providers aren’t equipped to manage.

GLP-1 medication and discontinuation considerations

Some people discontinue GLP-1 medication because of side effects, cost, access, or personal preference.

Weight regain can occur after discontinuation, making a structured maintenance plan important.

Weight loss can include lean mass as well as fat; adequate protein and resistance training can help preserve strength.

Long-term treatment decisions are individual and should consider benefits, risks, tolerability, and health goals.

Wegovy carries a boxed warning for thyroid C-cell tumors based on rodent studies; it is unknown whether this risk applies to humans.

We provide a structured, physician-led plan for clinically appropriate tapering and long-term weight maintenance.

How Our Program Works

Enroll in Program
Clinical
Screenings
Lifestyle
Coaching
Medication
Review
Built-In
Off-Ramp
Sustained
Maintenance

What You'll Get

An individualized, physician-guided medication-transition plan when clinically appropriate
15 scheduled visits with your medical provider, clinical team, and health coach
Access to our mobile app and private digital community for daily support
Structured low-carb nutrition and movement plans personalized to you
Weekly group coaching sessions to reinforce progress and connection
Lab work and real-time monitoring

Not sure yet? Book a call to ask questions and see if this is a good fit.

Medication Is One Part of Your Metabolic Health

Weight, blood sugar, sleep, stress, nutrition, movement, and medication influence one another. We look at the whole picture so your off-ramp supports sustainable health beyond medication.

Metabolic disease shown in the roots of a tree, with thirteen connected conditions arranged along the branches Dyslipidemia Sarcopenia& arthritis Migraines Acidreflux Type 2diabetes Dementia Fattyliver Cancer Heartdisease High bloodpressure Stroke PCOS /ED Obesity
Toward Health multidisciplinary care team

A note from Dr. Tro Kalayjian, Founder

“I used to weigh 350 pounds. Even as a doctor, I couldn’t outthink the cravings, the emotional eating, or the grip ultra-processed food had on me. I tried everything until I finally faced the real problem. It wasn’t just about calories or willpower. I had to confront the addiction, the years of failed diets, and the emotional triggers that kept me stuck. That turning point became the foundation of this program. Now, it’s my mission to help others see they can break free too.”

Take the Next Step

GLP-1s might be a starting point, but they should not define your future. We help you take back control of your health, with or without medication.

This program is HSA/FSA eligible.

$500 registration fee
$500/month for 6 months*

*Participants are automatically enrolled in our Maintenance Program after 6 months, with the flexibility to cancel at any time following the initial program term.

Care Team

Every patient receives a dedicated doctor, dedicated health coach, and dedicated care coordinator, with real-time remote monitoring, urgent issue escalation, and coordination with existing medical teams.

Dr. Tro Kalayjian, founder of Toward Health

Where our clinicians have trained, taught, researched, and led.

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  • Yale Training + invited lecture
  • Stanford Medicine IRB/Data Agreement
  • Wake Forest School of Medicine Coauthored research
  • Greenwich Hospital Grand Rounds
  • University of South Florida Education + research
  • UC Santa Barbara Invited lecture
  • University Hospitals Invited lecture
  • Virginia Commonwealth University Medical Grand Rounds
  • The Obesity Society Invited lecture
  • AAHPO Invited speaker
  • SMHP Founding board
  • Coalition for Metabolic Health Advisor
  • Montefiore Clinical experience

Start with
The Food Relationship Fix

Our $199 webinar to help you take control of emotional eating. Available now in the Toward Health app with lifetime access.

The Food Relationship Fix clinical and coaching team

Step Off Medication With Confidence.

Build the support and skills to maintain your progress beyond GLP-1 medication.

Talk with our concierge team

Choose a date and time below for a free 20-minute discovery call with our team.

This is not a medical appointment. For new, non-clinical inquiries only. Existing patients should use their secure care channel or call (845) 397-2873. Do not include medical information in the scheduling form. For a medical emergency, call 911. Review our Privacy Policy and Terms. For scheduling help, call (845) 397-1115.

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